Leiden Genome Technology Center
We are specialized in next-generation sequencing (NGS) with a particular focus on single-cell sequencing and spatial transcriptomics
Services
The main goal of LGTC is to support scientists with their research questions about genomics and transcriptomics.
Single Cell Sequencing
Single-cell sequencing allows you to measure gene expression or chromatin accessibility simultaneously on thousands of cells
Spatial Transcriptomics
The LGTC counts with 2 platforms for spatial transcriptomics from 10x Genomics: the Xenium in situ platform and the Visium CytAssist platform.
PacBio
The LGTC installed the PacBio Revio platform in March 2024. The Revio platform offers affordable, high-throughput, highly accurate long read sequencing.
Oxford Nanopore
The LGTC installed the PromethION 24 in January 2023. The PromethION 24 offers flexible and affordable on-demand sequencing.
Additional Equipment
The Leiden Genome Technology Center has equipment that can be used for many different applications and is available for general or shared use. We also provide material for specific protocols.
News and courses
Scale Bio and LGTC Grant Program
Are you ready to elevate your single cell RNA experiments and leave traditional methods behind? With Scale Bio’s latest QuantumScale platform, we are pioneering a new era in single cell analysis—enabling the analysis of a much larger number of cells through massively parallel barcoding, all while improving workflow efficiency data quality. You now…
Training and Eduction
Leiden Genome Technology Center (LGTC) staff organize several courses and lectures every year for members of the Medical Genetics Centre (MGC). Single cell data analysis – Next edition in October 2024This week-long course covers the practicalities of single-cell sample preparation and analysis, with a particular focus on single-cell RNA-sequencing (scRNA-seq)…
Newsletter September
Demo instrument – BD RhapsodyThe LGTC is currently hosting a demo device of the BD Rhapsody Single-Cell Analysis system and scanner.The sales team at BD Rhapsody is offering discounted reagents during the demo period for interested users. If you think this platform might be suitable for your research question then…
Team and Contact
Dr. Susan Kloet
Head of the LGTCOur team specializes in the validation and implementation of single-cell and single-molecule sequencing technologies for researchers at the LUMC as well as our international collaborators.
Shantie Jagmohan-Changur
Lab manager
Dr. Roberta Menafra
Bioinformatician
Dr. Natalia Escobar
Researcher
Emile de Meijer
Scientific supportRolf Vossen
Scientific supportYavuz Ariyurek
Scientific support