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FlexArrayer
System
FlexGen B.V was founded in 2004, as a spin-off from Dutch Space (part of the EADS consortium) and the Leiden University Medical Centre. This made the development of the FlexArrayer possible. The Leiden Genome Technology Center had the first operational FlexGen FlexArrayer in the world, installed and inaugurated in January 2009. It is a system to synthesize custom made microarrays. It uses laser technology to synthesize oligonucleotides on a microarray slide by specifically activating the spots were nucleotides have to be built. See the FlexGen website for more information on the FlexArrayer, its technology, and applications.
Applications
The main focus at the LGTC is to use FlexArrays for hybridization capture followed by next generation sequencing, but the system can be used for any custom microarray project.
FlexSelect: customized probes for hybridization capture with a similar workflow as Agilents "SureSelect". Probes can be made for short regions like exons. Multiple samples can be pooled and sequenced (next generation).
Flex2SNP: customized probes that will target SNPs and make it possible to get sequence data from it. One array can target ~5000 custom SNPs.
FlexGen and the LGTC are still optimizing the protocols, but when you have a project for the FlexArrayer you are welcome to discuss it with us.
More information coming soon
More information on the FlexArrayer and its applications will soon be added to the website.
More information? Questions?
Go to www.FlexGen.nl
Contact the LGTC
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